DPCstruct | MC50593

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)141 ± 24 aa
Standard deviation of domain lengths23.73
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score74.65
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)39.72
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S3IT37 1-170 MIFYIFHQQIQQTVLDTLTPDDIRVLIATVDEDSRKGGFERVFPTAKSSKYLKFFEQPRYYNLLLNQWVQRYNKMEARGVALLDSFC…
T1JAJ5 183-290 MERHEYLLTVLANPTADDIRQLVLAEDERSRAGQYICVYPTHHTNRYHKYFDRARYYNHLFDAWETRYHSCRDDGIQKLIEACKQGL…
A0A7J7KL05 126-280 None
A0A7J7IXU6 1-155 None
A0A1Y1KUU5 346-476 None
A0A2S2R1C1 58-230 None
A0A146MB87 845-975 None
A0A7R9HAF8 177-316 None
Q95TA0 11-112 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.