DPCstruct | MC50575

Metacluster Properties and Pfam Annotations

Number of structural domains777
Mean domain length (aa)143 ± 26 aa
Standard deviation of domain lengths26.42
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score88.70
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)18.77
Pfam Score97.77
Assigned Pfam label(s) CL0052- CL0126- PF13382- CL0105- CL0507

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A099I8E5 22-167 None
E5Y4F1 27-192 None
A0A455SEY3 11-175 None
A0A2V8TJV4 8-159 None
A0A4W5LQ82 30-180 None
A0DTW1 1-140 None
C3YIP1 570-713 None
A0A4D4L2L8 155-290 None
A0A4D4LDL8 2-118 None
A0A2X2K232 2-101 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.