DPCstruct | MC50575

Metacluster Properties and Pfam Annotations

Number of structural domains777
Mean domain length (aa)143 ± 26 aa
Standard deviation of domain lengths26.42
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score88.70
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)18.77
Pfam Score97.77
Assigned Pfam label(s) CL0052- CL0126- PF13382- CL0105- CL0507

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A827F8V2 42-172 GQGQMLSAGCADLVLTNALIIDYWGIVKADIGVKDGRIFAIGKAGNPDIQPNVTIPIGVSTEIIAAEGRIVTAGGVDTHIHWICPQQ…
X1RT83 24-163 APASGQEKTPKPQILFINCNVFDGKADKLATNRRVLVEGNLIKTIGDKGLKGAKHAKVIDCGGRTLMPGLIDSHSHFNVEIDGGLKE…
A0A2A4I5V5 370-533 None
A0A2J8ABX4 8-161 None
A0A511NDW4 35-170 None
A0A3D1Q9B6 18-101 None
B5IKJ1 7-149 None
G8S4B6 61-198 None
D4KYQ0 2-127 None
A0A1H4E3I6 7-104 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.