DPCstruct | MC50539

Metacluster Properties and Pfam Annotations

Number of structural domains150
Mean domain length (aa)73 ± 9 aa
Standard deviation of domain lengths9.35
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score90.42
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)36.80
Pfam Score100.00
Assigned Pfam label(s) PF14206

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6L8W9Q4 2-76 KYACPCCSYLTFDEMPAGSFDICPVCYWEDDPVQSKDPNFVGGANGVSLIEAKANFLKFGAVKKECQRYVRQPLP
A0A2A8TEJ8 1-52 MKYTCPCCGYKTLDEEPPGTYDICEICFWEDDGYQYEHPDEDGANYVSFREA
A0A7X9KZF4 6-72 None
A0A4Y9T3W6 78-151 None
A0A1M3E1B0 4-75 None
A0A413S633 8-69 None
A0A6G8FX20 71-142 None
A0A5J6SN01 2-68 None
A0A433DH09 3-82 None
A0A3B9IXN8 62-140 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.