DPCstruct | MC50467

Metacluster Properties and Pfam Annotations

Number of structural domains1879
Mean domain length (aa)163 ± 28 aa
Standard deviation of domain lengths27.65
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score80.38
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)11.70
Pfam Score84.20
Assigned Pfam label(s) PF07833- CL0689- CL0041- PF10572- PF17217

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A497AQX1 25-178 AYEFITGTTTFTITTDVSGTMSTDDGRVRIEWPTASVTCTVVMTYTPLGRPGENLPTFLSFGGIAFDLQATDCNGDPVEAFLKPLTL…
A0A1G2XRD8 384-521 SILVASGTNICNWGEAAEDTDIDMINSARITFDSSMAGTLTGNLLCDGRSDLPVNSFRVIGAWDFQNTASVSNVGIVVRYDDLLSAQ…
A0A1S3Q403 495-688 None
A0A668RT01 51-219 None
A0A668S4D2 90-256 None
A0A673W016 609-814 None
A0A7W1EM85 11-175 None
A0A527V8Q7 508-622 None
A0A7R9KIB6 265-451 None
A0A0Q5V2Y5 28-191 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.