DPCstruct | MC50275

Metacluster Properties and Pfam Annotations

Number of structural domains151
Mean domain length (aa)371 ± 72 aa
Standard deviation of domain lengths72.10
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score88.59
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)20.43
Pfam Score71.66
Assigned Pfam label(s) CL0126- PF10415- PF08328- CL0105- PF10397

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3M8FY30 7-392 DDVLLDRELFPFDILATRAHVKGLASIRLIEEADASRINTALVELDRLFASGAFVLDERYEDGHSAIESFLVDKLGEAGKRVHLGRS…
A0A420IRM5 85-536 AEYRIETDAFGEVKVRADRYWGAQTERSLGNFKINQPQDRMPSPIIKAFGILKGAAATVNMRYGLDSTIGKAIQEAAKEVADLKLID…
A0A1Q9C215 379-664 None
A0A1T3P777 238-685 None
A0A258L726 2-304 None
A0A812P1I4 382-802 None
K2DPL1 27-466 None
A0A0K2RUM3 3-278 None
A0A2E1V596 3-277 None
A0A1I8FKZ5 15-424 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.