DPCstruct | MC50205

Metacluster Properties and Pfam Annotations

Number of structural domains41
Mean domain length (aa)232 ± 30 aa
Standard deviation of domain lengths29.64
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score81.08
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)23.03
Pfam Score100.00
Assigned Pfam label(s) CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2A9NJ13 111-346 VRIKNGWYVLINAEATTYLPTDSTTTEEGEFRPPPLVPCYFGPFDQQQKHEMKMFDTLNMSAYFKESQSVVFNAGAPVWAIDWCPIH…
F6U313 315-528 WKSLNLTKNLREQLHSHWEFPEWIPSASKWHLLTDTEAAPYLPRELKSPLFSVQREGLPEDEALYRINRFGSLTPHGERWDVSFFTG…
A0A5K3EY59 12-232 None
F2SF41 62-362 None
A0A0B7N8S0 10-258 None
C1N9E0 182-381 None
A0A6A6GKG8 41-271 None
A0A7E4S8T8 608-807 None
A0A2J7PRQ7 295-567 None
A0A183KPU8 175-387 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.