DPCstruct | MC50204

Metacluster Properties and Pfam Annotations

Number of structural domains76
Mean domain length (aa)179 ± 48 aa
Standard deviation of domain lengths48.39
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score72.91
Mean fraction of residues predicted as intrinsically disordered0.43
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)23.65
Pfam Score100.00
Assigned Pfam label(s) CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2A9NDY2 1-146 MTSNTSGPRFRPFASPNHHVTKGRYITSNDPRGYIPVYEYPLNGQWIMMDIDDGYILWTGIWKALGNSKADIVKMIDSQPDLASVIR…
A0A0L0HPY0 186-286 GLYEATYSNVPVYEMASPNGVGVMRRRHDSWMNATHILKAAGMEKSRRTKVLEREIHQGEHEKIQGGYGKYQGTWIPLYRARELAAE…
A0A2H3BTG8 1-262 None
A0A1V2LLD2 108-310 None
Q6FJB4 119-256 None
H2AMQ0 214-365 None
A0A1E4SMC6 177-311 None
G4TKQ4 1-235 None
A0A1Y1W668 9-210 None
A0A167T2T5 315-503 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.