DPCstruct | MC50189

Metacluster Properties and Pfam Annotations

Number of structural domains52
Mean domain length (aa)233 ± 66 aa
Standard deviation of domain lengths66.42
Length coefficient of variation0.29
Mean AlphaFold2 pLDDT confidence score75.22
Mean fraction of residues predicted as intrinsically disordered0.73
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)26.48
Pfam Score80.53
Assigned Pfam label(s) PF09405- PF13821- CL0097- CL0449

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A4VCR5 194-429 FRREAERQHRLERRRQLADQQRRERSRPIRVLEAEQRERALDKPIDSSNKGFAMLQMMGYKPGMAIGKQGDGRTEPIRPELNQGRAG…
A0A672L037 1-153 MVKREKEALKKEALRKEKNAQNRQKSYKEQERESREAALQSSLSSQNKGFALLQKMGYKAGQGLGKQGAGRVEPVPLNIKTDRGGIG…
A0A6P5MZK4 22-135 None
F0XWE2 628-836 None
A0A7S0H149 135-325 None
A0A1X2HS01 5-265 None
B9WC37 35-267 None
A0A7G2ESB1 631-828 None
A0A5J4NLD6 1-165 None
B6JXR9 1-229 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.