DPCstruct | MC50149

Metacluster Properties and Pfam Annotations

Number of structural domains281
Mean domain length (aa)180 ± 31 aa
Standard deviation of domain lengths30.51
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score78.78
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)18.62
Pfam Score56.42
Assigned Pfam label(s) PF08590- CL0020- CL0537- CL0192- PF01713

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A146ICL9 223-422 None
A0A7G2CSI0 573-766 None
A0A7R9W4I8 8-233 None
A0A074YXI1 15-175 None
A0A2G5BD69 20-183 None
A0A813KKU2 300-458 None
R1DDK8 428-595 None
A0A4S4LNT3 882-1069 None
A0A4S4LXI0 473-637 None
A0A4S4M5Z6 467-667 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.