DPCstruct | MC50149

Metacluster Properties and Pfam Annotations

Number of structural domains281
Mean domain length (aa)180 ± 31 aa
Standard deviation of domain lengths30.51
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score78.78
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)18.62
Pfam Score56.42
Assigned Pfam label(s) PF08590- CL0020- CL0537- CL0192- PF01713

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5B1QTW5 40-213 QPPAAEHVKIGAPETEWRVRAGDSAGTELRNRAQEAFKVMREEREKARKARVAGNRSDAQLHNRLADERRVQAEKLNKDAAEVLYRE…
A0A7C9AVI6 8-150 LQDNAAFNFVNALEDFLWAFELRATASWLFQLAVNRGIYQHDVFRVAEGDWGADFRKLSAGAALVGLTLWLDHMQDASLEGSPESPK…
A0A7S2XLX6 311-478 None
A0A7R9PXR1 338-526 None
A0A6S7GWR7 383-576 None
A0A6S7G597 765-972 None
H0EHG9 40-250 None
A0A835RT24 17-173 None
A0A831YBM9 15-198 None
A0A0S6XJI7 7-101 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.