DPCstruct | MC50077

Metacluster Properties and Pfam Annotations

Number of structural domains63
Mean domain length (aa)97 ± 16 aa
Standard deviation of domain lengths16.41
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score68.15
Mean fraction of residues predicted as intrinsically disordered0.73
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)49.92
Pfam Score98.67
Assigned Pfam label(s) PF08474- PF01530

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A834PEX3 1-117 MLYGAGNGGLTILNYRCPIPGCDGSGHATGKFLSHRSASGCPIANRNKMRVLESGGTVEQHKAAIAATTAMKFEGVNCPTPGCDGIG…
A0A443SHV2 23-94 TKCPTPGCNGTGHSTGLYSHHRSLSGCPRKDKITPEILAMHETILKCPTPGCNGRGHVNSNRNTHRSLSGCP
S4RC21 337-429 None
A0A016TMM3 181-293 None
A0A182JH64 59-177 None
A0A4W4HHY5 119-234 None
A0A564Y1T6 1-96 None
A0A3Q0KSH2 219-298 None
A0A7F8RR31 454-561 None
A0A4U5UN68 403-492 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.