DPCstruct | MC5005

Metacluster Properties and Pfam Annotations

Number of structural domains2299
Mean domain length (aa)302 ± 76 aa
Standard deviation of domain lengths75.62
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score89.14
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)13.60
Pfam Score98.04
Assigned Pfam label(s) CL0489- CL0022- CL0289- PF02729- PF03711

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7V2X8G0 113-356 None
A0A444FTX2 11-304 None
A0A2V0PE69 18-309 None
A0A2V7MNK4 229-515 None
A0A0K9PQ00 31-367 None
A0A4S4B4L7 19-261 None
W3VHX7 223-599 None
A0A1N7IS26 67-226 None
A0A398DLG0 12-157 None
A0A0E0L9V6 125-412 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.