DPCstruct | MC5005

Metacluster Properties and Pfam Annotations

Number of structural domains2299
Mean domain length (aa)302 ± 76 aa
Standard deviation of domain lengths75.62
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score89.14
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)13.60
Pfam Score98.04
Assigned Pfam label(s) CL0489- CL0022- CL0289- PF02729- PF03711

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H3E2U2 593-986 None
H3EA32 95-477 None
A0A3D8K0K3 9-255 None
A0A0J6WB79 425-775 None
A0A3C0E182 34-373 None
V6M3D6 51-292 None
A0A1Q6RCB8 1-148 None
A0A8B3HJM5 85-320 None
S9WYA6 236-571 None
A0A803LTV0 30-296 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.