DPCstruct | MC50032

Metacluster Properties and Pfam Annotations

Number of structural domains218
Mean domain length (aa)326 ± 73 aa
Standard deviation of domain lengths72.51
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score88.67
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)22.55
Pfam Score80.33
Assigned Pfam label(s) PF00330- CL0020- PF04412- CL0159- CL0364

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
L1KTH2 44-421 None
A0A377DFG9 7-297 None
C1FEI6 18-393 None
A0A6F9C8T1 2-271 None
A0A135V2H8 192-425 None
A0A395GZ72 489-864 None
A0A3Q0JB04 1-301 None
X1HP62 20-274 None
A0A850R341 14-361 None
A0A4R0RNW5 26-407 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.