DPCstruct | MC50032

Metacluster Properties and Pfam Annotations

Number of structural domains218
Mean domain length (aa)326 ± 73 aa
Standard deviation of domain lengths72.51
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score88.67
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)22.55
Pfam Score80.33
Assigned Pfam label(s) PF00330- CL0020- PF04412- CL0159- CL0364

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A448Z0I3 301-729 None
A0A2V9Y515 21-342 None
A0A445GEU3 62-329 None
A0A5C7IV68 184-405 None
A0A2U3RQY8 2-275 None
A0A249Q1U5 1-236 None
A0A428Q5K0 3-167 None
A0A7W1AGS8 2-292 None
A0A7X7Y8Q2 41-461 None
A0A7I8JTK9 190-593 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.