DPCstruct | MC4999

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)358 ± 49 aa
Standard deviation of domain lengths48.84
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score71.76
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)32.15
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0M9VUJ5 20-364 AAAEIPVAISLYDLLHNSLILRHVAPYLPIASLLHLAAASRYFRHLILQTPGVFRHLDLSRVQSLQPEYRRIRPDDSITEDDFYSGP…
C0NYT1 238-639 LSHTPASISLLDLLSNSLILDHIAPYLSISSLLSLASTCTAFHSIIMDTPYVFRHMDLTTCRAAQPPPSMGPIDAGGEVWRSERMDE…
E5A8Q2 5-279 None
A0A0F4YWP9 79-450 None
L7J298 1-406 None
A0A168DX04 75-465 None
R1ER50 384-662 None
Q2GTF1 22-415 None
A0A232M0U7 99-443 None
A0A5J5EWP3 107-466 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.