DPCstruct | MC49964

Metacluster Properties and Pfam Annotations

Number of structural domains374
Mean domain length (aa)184 ± 38 aa
Standard deviation of domain lengths37.78
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score81.18
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)12.61
Pfam Score64.98
Assigned Pfam label(s) PF16074- PF07963- PF15980- CL0327- PF16152

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H0RD27 4-182 None
A0A553ZXR8 1-140 None
A0A7W3YBM5 7-144 None
A0A415E4T8 4-160 None
A0A1Y6EGN9 134-342 None
A0A2E6M0E9 2-205 None
A0A2M7G279 10-216 None
A0A1V5K172 6-181 None
A0A328RB09 1-198 None
A0A6N7WYH3 11-161 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.