DPCstruct | MC49964

Metacluster Properties and Pfam Annotations

Number of structural domains374
Mean domain length (aa)184 ± 38 aa
Standard deviation of domain lengths37.78
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score81.18
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)12.61
Pfam Score64.98
Assigned Pfam label(s) PF16074- PF07963- PF15980- CL0327- PF16152

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A379XMG9 6-148 NTRQLSLEDEIWQRTYTIAKHLQRAGYCHGHCIGEGLHLAEQGQCVIVQWDGNNNGVWDTIPAKEADQTGFRVKDNVLETLRGATSC…
A0A352F4F4 8-190 SSNKFERGFSLLELTIAMAISLAVLAAASTLLATSLRTRTRENTRSEALASAQRTLNIMTREIGNSGYGLNDNGIVTADSGVSSIRV…
A0A1G2XDQ6 1-275 None
A0A371JGV3 23-214 None
A0A2E1H5I0 1-200 None
A0A1G1YYI4 13-162 None
A0A3D3P0C9 36-260 None
A0A367ZCU4 7-198 None
R6ZAV4 1-166 None
A0A182TIY4 94-280 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.