DPCstruct | MC49953

Metacluster Properties and Pfam Annotations

Number of structural domains28922
Mean domain length (aa)283 ± 60 aa
Standard deviation of domain lengths60.41
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score81.74
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.36
Mean intra-cluster sequence similarity (%)10.59
Pfam Score82.37
Assigned Pfam label(s) PF02751- PF10395- PF19755- PF00045- PF03736

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A654HLW4 192-494 None
C4M641 155-354 None
A0A654HLF1 1-240 None
A0A654HIX2 36-472 None
A0A654HG56 323-595 None
A0A654HEI6 137-438 None
A0A654HDQ0 261-540 None
A0A1G3MZV6 39-300 None
A0A1Q6XR43 9-338 None
A0A1V2LM29 5-197 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.