DPCstruct | MC49953

Metacluster Properties and Pfam Annotations

Number of structural domains28922
Mean domain length (aa)283 ± 60 aa
Standard deviation of domain lengths60.41
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score81.74
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.36
Mean intra-cluster sequence similarity (%)10.59
Pfam Score82.37
Assigned Pfam label(s) PF02751- PF10395- PF19755- PF00045- PF03736

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q2X2A5 27-256 None
A0A414R6A1 4-171 None
A0A414RCT0 2-226 None
A0A1Z9QND3 27-379 None
E0NS47 178-469 None
A0A0S8ANM6 2-203 None
A0A0S8ACD6 4-255 None
A0A849R339 619-918 None
A0A849R1I0 38-355 None
A0A146I3Y2 26-300 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.