DPCstruct | MC49953

Metacluster Properties and Pfam Annotations

Number of structural domains28922
Mean domain length (aa)283 ± 60 aa
Standard deviation of domain lengths60.41
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score81.74
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.36
Mean intra-cluster sequence similarity (%)10.59
Pfam Score82.37
Assigned Pfam label(s) PF02751- PF10395- PF19755- PF00045- PF03736

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W9YWI4 430-701 None
A0A2S7T8M3 19-257 None
A0A2S7T6R6 278-602 None
A0A2S7T5K6 49-310 None
A0A432M628 121-384 None
A0A7V3FN58 3-266 None
A0A7V3FMD7 22-281 None
A0A183EFJ3 133-329 None
A0A183EF34 49-345 None
A0A183EBN8 13-237 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.