DPCstruct | MC49953

Metacluster Properties and Pfam Annotations

Number of structural domains28922
Mean domain length (aa)283 ± 60 aa
Standard deviation of domain lengths60.41
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score81.74
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.36
Mean intra-cluster sequence similarity (%)10.59
Pfam Score82.37
Assigned Pfam label(s) PF02751- PF10395- PF19755- PF00045- PF03736

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1M3AEX5 29-375 None
A0A6J1W987 2-267 None
A0A212KIF3 1-389 None
H2M4V5 22-508 None
A0A7W1V7N0 47-308 None
A0A1E5WJR5 17-195 None
A0A1E5WFR3 178-459 None
A0A6B1A874 44-315 None
A0A6A7LUQ7 299-587 None
A0A6A7LQ41 162-404 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.