DPCstruct | MC49953

Metacluster Properties and Pfam Annotations

Number of structural domains28922
Mean domain length (aa)283 ± 60 aa
Standard deviation of domain lengths60.41
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score81.74
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.36
Mean intra-cluster sequence similarity (%)10.59
Pfam Score82.37
Assigned Pfam label(s) PF02751- PF10395- PF19755- PF00045- PF03736

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A353P7W8 521-762 None
A0A7S0Y526 1-240 None
A0A3P6AZZ8 45-339 None
A0A3P6AWK3 9-196 None
A0A7K0J1U0 28-308 None
A0A2Z7D0L7 132-361 None
A0A2Z7CMM8 113-344 None
A0A2Z7C9Y5 54-353 None
A0A2Z7C8S1 13-273 None
A0A1R3KWX1 73-320 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.