DPCstruct | MC49953

Metacluster Properties and Pfam Annotations

Number of structural domains28922
Mean domain length (aa)283 ± 60 aa
Standard deviation of domain lengths60.41
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score81.74
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.36
Mean intra-cluster sequence similarity (%)10.59
Pfam Score82.37
Assigned Pfam label(s) PF02751- PF10395- PF19755- PF00045- PF03736

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1E3GRG8 2-294 YVHTPFPNIVYALDLNEDGAIKWKYEPKQDPNVIPVMCCDTVNRGVAYGDGKIILHQADTTVVALDAKTGAVAWSVKNGDPAIGETG…
A2DVG8 20-305 PGMTVGCIAYSPDGSQVAFSSSPNEMVVKNVINGEDVQTLQQSVTSHPLISCFFHPIEEDFLFTIYKDGHMFLYDMQTNEVLKTSRH…
A0A0E0GFR5 80-497 None
A0A0E0GGT2 17-316 None
A0A0E0H2B9 21-420 None
A0A453DTX6 159-483 None
A0A446IQ14 246-563 None
A0A7S2U5Q0 124-512 None
A0A5D8YNT9 79-304 None
A0A5D8YQG5 311-535 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.