DPCstruct | MC49949

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)122 ± 18 aa
Standard deviation of domain lengths18.20
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score90.58
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)44.00
Pfam Score100.00
Assigned Pfam label(s) CL0465

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A2DT35 143-276 NDLETFIFITEKEGFDKNQQLQSSLYPESEEGYSLLELCCYHGAVDCFKLLRTKFNSEITEQCLWFSFLGGNQDIMSECLKYQEPDY…
A2DJB8 1-112 MNNDFEKFNQFTERDGFDKDQRLYSELYPYSSEGYSLLELCCYHGAVDCFKLLRTKFSSEITQKCLHFSFLGGNPEIMSECLKYQKP…
A2DAU1 105-238 None
A2FXG9 105-193 None
A2FEY5 1-81 None
A2F6W9 1-136 None
A2F5B1 73-195 None
A2E339 89-221 None
A2DQN1 1-136 None
A2F0H2 136-245 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.