DPCstruct | MC4994

Metacluster Properties and Pfam Annotations

Number of structural domains56
Mean domain length (aa)114 ± 17 aa
Standard deviation of domain lengths17.11
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score79.93
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)34.49
Pfam Score98.89
Assigned Pfam label(s) PF00696- CL0491

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
J9EM48 15-118 LVNVERFPLVLYKRILRLHYGLPKEMRIIGDQYIKNEFRKHKNVSPEQAVVFLKEWREYSTVLSKQLSSRGIAKGILGVNLNSTLLD…
C0NCP9 2-112 ANPLPITPSSRQQSALLPPLQLYRRLLRVHRKKLPKDMRLLGDEYVKNEFRAHRNVDNPIHIVGFLTEWQLYAQKLEGDTWQGEKLD…
A8J8W4 10-108 None
G0UAV3 9-146 None
A0A4S2MZU6 7-132 None
A0A066WEJ2 1-150 None
A0A507FSM8 1-126 None
A0A0F4YVM0 14-124 None
A0A5E4B7W9 5-98 None
A0A4P9W0L3 1-95 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.