DPCstruct | MC49914

Metacluster Properties and Pfam Annotations

Number of structural domains294
Mean domain length (aa)158 ± 35 aa
Standard deviation of domain lengths34.54
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score83.81
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)19.29
Pfam Score87.72
Assigned Pfam label(s) CL0175- PF12251- PF07929

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q4IKW2 2-175 IDQFKLTFRGTHHPPVWIRIEVDQNMTFRGLHELIQAAFDWGDIMLHDFEVPNPQNTDKQVGGLDLNHLVEFAVKYMLPTKHIGPAD…
A0A7I9XQD0 39-212 RPRRKQPVTLRVRADLAETKPPVWRRLELASDLMLDDVHLIIQTAFGWTDSHLHQFGSGPSYRSPGTEYYLCPFMVEDGDDGVSEEQ…
A0A413CZI9 91-233 None
A0A1G7CIN3 18-181 None
A0A3N4KDY3 136-323 None
A0A2R6KH01 11-156 None
A0A0C2E5R5 109-266 None
A0A1K2FDS9 4-124 None
A0A3N4IHU3 91-312 None
A0A5C8K652 295-429 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.