DPCstruct | MC49903

Metacluster Properties and Pfam Annotations

Number of structural domains116
Mean domain length (aa)202 ± 32 aa
Standard deviation of domain lengths31.66
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score81.63
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)20.48
Pfam Score75.45
Assigned Pfam label(s) PF18684- PF06101- CL0063- CL0293

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W7IKD7 16-194 FPATVQRSTTAKFEWVWSDAGSGAHGDVAVWRPVPEDGWYALGDYAQGDYTKPAALAVTVRQVGLSDRPLLKAPVGFTQVWNDKGSR…
A0A345H8L7 1-145 MLKIKISIVNSFELAWWDKGSGGNMDGAFYNPINIPIGFHTIDSYGQSNYDFPSGSILVVKDNVPDVLAHPVDFKLIYKDTGSRASM…
A0A7S2JNS4 177-377 None
A0A6S7H7F0 891-1078 None
A0A849MIX0 36-230 None
A0A2D9NGJ6 273-461 None
A0A0C9TMA4 188-352 None
A0A2N9I4W2 2-152 None
A0A6P8CFW6 199-404 None
A0A446JYC2 789-996 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.