DPCstruct | MC4989

Metacluster Properties and Pfam Annotations

Number of structural domains7
Mean domain length (aa)283 ± 20 aa
Standard deviation of domain lengths20.33
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score63.39
Mean fraction of residues predicted as intrinsically disordered0.66
Mean length-normalized TM-Score0.20
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)20.09
Pfam Score88.10
Assigned Pfam label(s) PF10453- CL0537

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Z5KIE8 1-285 MPLAEAPPVMYQYNNSYRQPVNNPNFLTNVSQPPLSTSMPVTSQWKCIPCDLVLESKPALERHTASHVTCTECSFQAAPKVVKAHHQ…
A0A0L6V319 1-265 MSYSPYAQHFSAHQLNNSTSSHRFRCEQCKQDYYNLIDLSVHLRNHAKCDYENCKFEALPDILDLHREDRHLIFKPGREPKPKSNPK…
A0A0L0G156 25-319 None
L5MA91 123-404 None
L1JT01 1-323 None
I1CSU0 22-276 None
A0A7I8VWV8 1-277 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.