DPCstruct | MC49888

Metacluster Properties and Pfam Annotations

Number of structural domains35
Mean domain length (aa)251 ± 38 aa
Standard deviation of domain lengths37.52
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score70.97
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)22.20
Pfam Score97.83
Assigned Pfam label(s) CL0149- PF05542

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2Z6MEF2 26-267 LLEYVKTVQPEFMELFVKRAPQPVVDAMRQTVTNMIGTLPPQFFSITINTVAENLAQLMYSVMMTGYMFRNAQYRLELQESLEQVAL…
R1F135 3-214 AEFAKTAPEAVQLAVKQTVAALLGQMPAEVADGAITATGQSLASLFFSMQMTGYMFRNAEYRRSLSTTLAAAEDEMAEAAALPPVKG…
A0A7S0BNB6 34-312 None
A0A7S0Y8J1 142-455 None
A0A067KY98 4-188 None
A0A6D2K8G2 171-422 None
A0A498IY38 138-367 None
A0A2R6PPF5 33-271 None
A0A200QV55 44-325 None
A0A1X1BJR7 131-384 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.