DPCstruct | MC49817

Metacluster Properties and Pfam Annotations

Number of structural domains103
Mean domain length (aa)150 ± 31 aa
Standard deviation of domain lengths30.91
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score87.78
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)37.28
Pfam Score97.44
Assigned Pfam label(s) PF13966- CL0059- PF13968

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A835IJW9 591-752 CWAEDPNSDAFKYHLARIRDYLWIAEDGMKMQNLGSQSWDAFFAIQAILACNLLEEYGPTLKRGHEFLKKSQVQENPQGDFRSMYRH…
A0A5J6SDC9 134-290 TINMLVRWHVEGPQSPAFQEHVSRITDYLWLGLDGLKMQGTNGSQLWDTAFAVQALLEAGAQNIPAFTDCLNQAHAYFEVTQVRDNP…
A0A5N5JBD8 215-355 None
K3Y8T4 30-190 None
A0A1E5UPY1 5-151 None
A0A2G5D0F0 368-564 None
A0A7V8VDQ5 293-476 None
A0A396HCQ5 76-229 None
A0A2G2X280 27-195 None
A0A1U8F763 4-148 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.