DPCstruct | MC498

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)183 ± 18 aa
Standard deviation of domain lengths18.40
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score80.44
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)25.38
Pfam Score100.00
Assigned Pfam label(s) PF10699

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2R7W362 439-617 SELWYSVYNLREPFTSHAVNMDIFEKHCFEHRKNTWIKENEGLKVRVSTFQRRVTDGLPTQVFSYTPLQTIDREYVCLEASQAILLV…
A0A453LDM3 2-164 GDWFHVFEIVGRSTGYSIRVQVKKGSSVTEVIVSPENKTVVSKDNFLRVNLIGDFVSHNSMPTFEDFYLVTPRKAGGDGQPQVLGDE…
A0A5E4GNU5 31-218 None
J9KKT5 86-305 None
A0A6A0A4C3 112-285 None
A0A0A9F5V5 1-163 None
A0A6P3Y5Y7 71-283 None
A0A6P6GK76 56-217 None
F2UNH3 248-420 None
A0A818IHG9 364-533 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.