DPCstruct | MC49792

Metacluster Properties and Pfam Annotations

Number of structural domains177
Mean domain length (aa)125 ± 18 aa
Standard deviation of domain lengths17.61
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score82.54
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)12.82
Pfam Score63.40
Assigned Pfam label(s) PF08750- PF16747

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A840UJZ6 35-174 THWVWVSADSKYGKLYAPDRVTVTSRKNGVPVRIEAWIKTTYSATGAAETVPAMKLSKEIPVASTLRYSLALVEINPQSRTLDYLEE…
A0A225MDH8 11-138 CFAANAFCAPSWVPLTVPGSTRYLVDSGSLRPGGDATTDIAVLAEFPQPLAAAFDARLHYRSTITGYRIDCANRYAWVLNVSYYASG…
A0A1X1Q8I6 209-317 None
A0A532E1E4 35-152 None
A0A5C6UH08 4-103 None
A0A318AQW3 2-133 None
A0A7M2Y9I0 33-178 None
A0A229FVZ0 41-172 None
A0A7X6CA08 52-161 None
A0A5F0WK33 4-109 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.