DPCstruct | MC49782

Metacluster Properties and Pfam Annotations

Number of structural domains415
Mean domain length (aa)191 ± 35 aa
Standard deviation of domain lengths34.68
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score90.59
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)17.97
Pfam Score68.71
Assigned Pfam label(s) CL0268- CL0220- PF07589- CL0103- PF00082

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q3P514 399-573 DVTVTMDANAGGFSARDIWRNDIAGVGRFTKQGSGELSLAGANTYTGGTLIEAGAVRAASANALGTGAVYINGGSLVTDANDAVNVA…
A0A1Q5A3A1 199-380 ASLTKQGPGTLIMTGDETYEGGTTVEGGKLSITGSHASSIDVKGGTLGGSGSVGDSVTVTSGVLRPGLASEEAAQLTGTSAGNVLNV…
A0A2P7BAV6 448-624 None
L7VTJ9 961-1171 None
A0A4Q2XB37 150-370 None
A0A4Q2X9M3 3-115 None
A0A4Q2XYL9 102-334 None
A0A6N7F0L8 389-599 None
A0A6N7EUE3 82-272 None
A0A0H5DSD7 548-738 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.