DPCstruct | MC4978

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)101 ± 12 aa
Standard deviation of domain lengths12.38
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score86.93
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)34.69
Pfam Score100.00
Assigned Pfam label(s) PF20370

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A397PE39 3-92 EAAAEQVDQEILEEKAASLTRAGRRVETALKAIRAYDAGEQPDADRGELLDEAARAVWALLIQRELCGFRDEKRTIEQYDIPRDVMV…
A0A1H0QFS5 7-98 RSGYAVLQDELAQEKASALGRLGRRLEDALAALAACPREDSDRETRRKLVEQAGYALWLFVVQRESCGFNDSVRMMRQYGVPKEVFA…
A0A1J5QM88 1-110 None
A0A1G5P1L5 1-120 None
A0A4U6C655 1-104 None
A0A525L119 2-82 None
I7ZBW4 3-96 None
F2A8E2 146-250 None
A0A4R3FCS4 68-174 None
A0A285R773 1-114 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.