DPCstruct | MC4977

Metacluster Properties and Pfam Annotations

Number of structural domains757
Mean domain length (aa)249 ± 56 aa
Standard deviation of domain lengths56.01
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score85.19
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)14.82
Pfam Score84.53
Assigned Pfam label(s) CL0020- CL0379- CL0305- PF00817- CL0105

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1H0PJ03 6-274 FAILTGLKEEIETLLAAIPDLKEVAGEQQSDVWYRGRIGSERGYGYSIVATLARDMGPVPATLLTQHIIARWNPAHIILLGIAGSFS…
A0A1U8CXV7 7-195 SIMLHELIKLLHHAKCQGVTIIRIGTSGGLGIEPGSVVITDTALDSFFKPQFEQVILDNVVVRSTELDKDLAEELLNCSKEIHDFPT…
A0A497P2P0 8-261 None
A0A538Q5N0 15-267 None
A0A538PYW0 9-263 None
A0A7R9L7I4 2-162 None
A0A519KCC2 119-372 None
A0A6P5H839 1-226 None
A0A7S4E1S7 30-284 None
A0A1V2LL59 413-682 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.