DPCstruct | MC49761

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)77 ± 9 aa
Standard deviation of domain lengths8.67
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score87.98
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)43.74
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S1GH23 3-78 IRRQALFLLLAALPLAASAAAPRTFQEAKKIGWKLYARQSVEFYCGCRYKGNRVDLASCGYVPRKNAKRAARIEWE
A0A378BQS8 12-66 FSQAKAAGVKVNADVPGDFYCGCKIDWQGKKGVIDLESCGYKVRKNENRASRVEW
A0A2G0Y4T9 2-88 None
A0A5E5Q4B0 3-79 None
A0A2W4MBA5 1-90 None
A0A1J8PY62 2-82 None
A0A5E6XB86 1-68 None
A0A376FGR1 12-84 None
A0A1H6K7F3 1-81 None
A0A6D0M1Y4 3-74 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.