DPCstruct | MC4974

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)73 ± 5 aa
Standard deviation of domain lengths4.57
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score88.21
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)39.86
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2I0GX04 25-96 KTRLIEGLRDQYLLSDLLKTARIPRSSFYYHRTTLSHKDKYAHIKQRIADLYHKHKGRYGYRRITVALKQSG
A0A3Q8WTL9 1-77 MRTLAVATLKSDYNLAVLLEIARLPRSTFYYHLRALNRPDRHAAVKALITEIFSSRQGRYGHRRIRLCRRQLKSEQF
A0A8A7MHW3 25-89 None
A0A554QED0 162-232 None
A0A1H9VFP2 29-100 None
A0A2V2KZ30 2-68 None
A0A315ZMS1 186-263 None
A0A198GNA4 18-96 None
A0A3D5U113 13-83 None
A0A2L0LVV8 42-123 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.