DPCstruct | MC49726

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)139 ± 15 aa
Standard deviation of domain lengths14.81
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score80.18
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)38.35
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0C3GQZ5 4-171 LESYVRHEKASQPQAAEIIHGPINLFDVALKGVESGYRQCFRFCLLTSPTTVIANLKAGKADYDPEERQRISGNKSLARDTAFQLLH…
A0A010S014 263-387 MPTRLSDYHSLCETLRSRQVDVLAGRSLRDIMRDMRQGKDDWDPDERRTIAGFKSLARDSAFRLLYALVLDLPGVSDQNMAFNATMF…
L7IZE3 442-577 None
A0A2P4ZB96 932-1088 None
A0A401L9T5 17-156 None
L2FPU7 1-129 None
A0A5N5Q310 1-137 None
A0A5N5PV47 88-224 None
A0A0M9ENV0 361-483 None
A0A1L9U1J0 54-181 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.