DPCstruct | MC49663

Metacluster Properties and Pfam Annotations

Number of structural domains96
Mean domain length (aa)123 ± 23 aa
Standard deviation of domain lengths23.36
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score89.42
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)39.38
Pfam Score100.00
Assigned Pfam label(s) CL0040

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Z2EPK3 274-417 RLIWLEMGVPPARLLPFGLKENFWEMGDSGPCGPCTEIHYDHVGGRDAGALVNADSPEVVEIWNLVHTLTGPGSHLLVVPGRSKGVA…
A0A1F6WC03 84-234 LGHFSLYEGKEQEVKDVMIESAWHYLTVCAGISPATLSATVHPQDATSQKIWERLGVRTVSNDKNVTFTPTQNRCGIRTEIVWRNPD…
A0A5A9NS70 34-168 None
A0A5B8MMV0 407-525 None
A0A2G3BE36 34-145 None
A0A1E1VX76 3-115 None
A0A380QCL3 1-95 None
A0A7V5LED0 118-236 None
A0A0G1QQQ3 141-270 None
A0A835RAS9 217-346 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.