DPCstruct | MC49642

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)99 ± 12 aa
Standard deviation of domain lengths11.70
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score91.54
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.91
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)46.93
Pfam Score100.00
Assigned Pfam label(s) CL0408

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Z2E2I5 34-129 AGQARLDGAFCAYTEKDKQDYLNKACEAGICNIEMESSVFAAMCRLSGLRAAVVCVTLLDRLNGDQLDTSQDVLHSYQQRPQILVGY…
A0A1U8CXV7 106-199 EGQGRLDGALCSFSSEKKLEYLKRAYNAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLNRLEGDQITVPHEVLLEYQRRPQQLISI…
A0A2A6BA99 131-229 None
A0A2P4XKK5 211-304 None
A0A183F8M5 2-91 None
A0A3P6I910 1-100 None
A0A1V9ZXS8 866-956 None
M7CD98 65-154 None
A0A662WPF0 574-675 None
T1KTE8 266-367 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.