DPCstruct | MC49638

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)107 ± 6 aa
Standard deviation of domain lengths5.74
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score77.11
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)46.92
Pfam Score100.00
Assigned Pfam label(s) PF12257

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Z2DZX4 1-112 MSVVITPGVGVFQVDRLLMILTKQRMIDNGIGVDLVCMGEQPLHAVPLFKLHNRTTPGDSRVGDDYNLPHWINHSFYTSKSQNSCSS…
Q4DPH5 634-737 LVLEECIQSRWDTNTGYIISIVTAGKGLYQVTNELSQTTCTRLFSIGIEKINIICMGRPPLHITPLFEYFSEDETLRSQYHLHVGQS…
A0A0D8XVQ7 210-319 None
A0A1I7WUY3 2-109 None
W2T8P7 367-476 None
A0A821JAS8 114-221 None
A0A0M3I3A8 492-602 None
A0A444T137 122-223 None
A0A812Y9J7 317-428 None
A0A1V8UKQ6 290-390 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.