DPCstruct | MC49631

Metacluster Properties and Pfam Annotations

Number of structural domains54
Mean domain length (aa)131 ± 17 aa
Standard deviation of domain lengths16.89
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score84.93
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)17.44
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
F2LSD3 13-138 YIEPKILPVCDALNAIAGVRTLWSCEGHAQRPSRPYIVFESSEAFAFQVHQLLESAMDRGALRYWWRMTANFRPSGRLQWLVEAPTI…
A0A4R4R9N0 49-179 HPKWREAIEPGVRSLVDAATRDWRLVTYDSCQGHLYPGLDLPPSERRVGILPRDRTEYARVAAALCRAVTAVATDLPAEVQVAVGRA…
A0A3E0PNA2 13-128 None
A0A497B181 5-111 None
A0A6J4K3I1 18-166 None
A0A2P9GYA5 11-113 None
A0A7V2RU05 4-127 None
A0A0F9N415 1-105 None
A0A1F7QN29 19-175 None
A0A1X4N416 72-210 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.