DPCstruct | MC4961

Metacluster Properties and Pfam Annotations

Number of structural domains226
Mean domain length (aa)225 ± 29 aa
Standard deviation of domain lengths29.23
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score74.18
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)18.15
Pfam Score99.49
Assigned Pfam label(s) PF06695- PF09335

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A067CFU5 505-744 None
A0A3N9X0E8 18-211 None
A0A7I8J0M0 1-247 None
A0A183EEQ0 13-231 None
E6U0A8 6-205 None
A0A2S4LPA2 2-219 None
A0A1Y2CWT2 11-265 None
A0A554LFA7 7-194 None
A0A0C3CBH1 71-361 None
A0A077ZXY8 29-290 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.