DPCstruct | MC49595

Metacluster Properties and Pfam Annotations

Number of structural domains384
Mean domain length (aa)264 ± 70 aa
Standard deviation of domain lengths69.86
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score77.00
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)16.05
Pfam Score79.77
Assigned Pfam label(s) PF04087- PF19422- PF16916- PF12972- PF10411

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y7WNQ0 2-167 None
A0A5N5D8I9 11-321 None
A0A446QPK3 2-171 None
A0A7J6ZVK4 546-840 None
A0A7J6ZQ79 313-555 None
A0A3M7SNI6 129-464 None
A0A0D2K9Z6 2-300 None
A0A661Y2J3 117-439 None
A0A2I2FIT0 11-291 None
A0A4Y6ES88 20-225 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.