DPCstruct | MC49595

Metacluster Properties and Pfam Annotations

Number of structural domains384
Mean domain length (aa)264 ± 70 aa
Standard deviation of domain lengths69.86
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score77.00
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)16.05
Pfam Score79.77
Assigned Pfam label(s) PF04087- PF19422- PF16916- PF12972- PF10411

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q3Y269 6-261 IIAGYVTGSMALLADGFHMATHAGALSVAAAAYAYAKRHARNPTYSFGTGKVGDLAGFASALILGLVALGIGIESVLRLFQPITVAF…
A0A0U5B005 3-191 IATAIRFAGLSIACSLFVFCMTGFITLLTGSLTVAAVELYSLLCAAASTAVFLTLRSGDSRYTDPSKKILLAALVFVVGGGLWIAFV…
A0A1J9QXB7 26-335 None
L5KEM1 2-250 None
M2R1D6 179-448 None
A0A1V2LJZ6 761-1168 None
A0A7K2B1L8 19-221 None
A0A3B9ZNS7 17-266 None
A0A7R9KE83 10-283 None
A0A2R4ZMT4 2-194 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.