DPCstruct | MC49591

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)100 ± 9 aa
Standard deviation of domain lengths8.77
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score82.74
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)40.39
Pfam Score100.00
Assigned Pfam label(s) CL0537

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
M3XXJ3 41-142 ILLLQNDPCLLPEVCLLYNKGEALYGYCNLKDKCNKFHVCKSFVRGECRLQKCKRSHQLIHATSLQLLQDQGLNIPSVVNFQIISTY…
A0A643BWZ1 12-107 QVCLLYNKGEALYGYCNLKDKCNKFHVCKSFVRGECRLPKCKRSHQLIHATSLQLLQDQGLNIPSVVNFQIIATYKHMKLHKMLQNK…
A0A3B4DFS0 134-229 None
A0A4W4FRT8 25-119 None
A0A060X4J6 134-235 None
A0A0S7FGM9 9-96 None
A0A3Q1BPI3 130-234 None
A0A803XKG4 63-168 None
A0A4W4FQ67 100-205 None
A0A1S3FLW0 98-215 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.