DPCstruct | MC49565

Metacluster Properties and Pfam Annotations

Number of structural domains34
Mean domain length (aa)189 ± 24 aa
Standard deviation of domain lengths23.96
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score77.86
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)27.96
Pfam Score100.00
Assigned Pfam label(s) PF20219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0D2HUP4 23-197 LFSAFLNGMSVVAQFVEVLQGSSALEEIGQKIHRELEAQTGLTAPKTFTKQVHKVIVHETSLAHEDGARHFHFLYHHDTDWRGYFFD…
A0A4R8Q2D2 6-146 PDGLARPLYGIVKYYMEKHQRKGHRFYLWHPDNIWHWRFDELLAATPLPNTFDAYSDDMDALVNVMKGARQALPEKHRSGVVFHLVI…
N4VTK2 6-147 None
A0A423VHR6 66-248 None
A0A1J9S4F3 7-213 None
W6YKK9 5-230 None
W9K458 1-156 None
A0A545W243 78-285 None
J4KQM4 36-222 None
I8TW13 11-189 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.