DPCstruct | MC49555

Metacluster Properties and Pfam Annotations

Number of structural domains427
Mean domain length (aa)110 ± 18 aa
Standard deviation of domain lengths17.76
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score85.01
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)22.56
Pfam Score100.00
Assigned Pfam label(s) CL0408

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q7JI13 2-113 PDPLDYTVGWICPVTTEYIAAQAFLDEKHAGPDDIPLHDHNDYTLGRVGRHNVVIAVLPLGEYGISSATGVAKDMLNSFHNVRIGLL…
A0A6A3WRS0 19-124 HLGVKAGQVANRVVSVGSISRAKLLAQLLDDAKFDTFESPRGFTTFTGKKKGVQVSIIATGMGVPNMDFVVRETRAVVEGPMIIIRF…
A0A5C6SYS5 299-442 None
A0A2X2S5D8 6-96 None
A0A2V7Y1Q9 1-117 None
A0A1V6RIR9 2-98 None
A0A845WAW3 1-79 None
A0A4Z0YPH5 433-543 None
A0A1L9TXV8 289-408 None
A0A2V5ISD1 2-99 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.